(05/24/09) NEW YORK (AP) - A woman in her 50s is New York City's second confirmed death linked to swine flu.

A spokeswoman for the city's Department of Health and Mental Hygiene says that the woman died over the weekend and had underlying health conditions.

Spokeswoman Jessica Scaperotti says people with chronic health conditions such as diabetes and compromised immune systems should seek medical advice.

She says there are 280 confirmed cases of swine flu in the city. Assistant public school principal Mitchell Wiener became the city's first death from the virus last week.

The city's first outbreak of swine flu occurred about a month ago, when more than 1,000 teenagers at a Catholic high school began falling ill following the return of several students from vacations in Mexico, the epicenter of the outbreak.