Police say a man was fatally stabbed around 12:45 a.m. just inside the 2 train station.
They were called to the scene at the intersection of East 241st Street and White Plains Road at around 1 a.m., where they found the man who had been stabbed in the torso.
He was transported to Montefiore Medical Center, where he was pronounced dead at around 2 a.m.
Police say it started when the two men got into an argument. The suspect is still at large.
Anyone with information regarding this incident should call Crime Stoppers at 1-800-577-TIPS (8477).
Subway service is back up and running at the 241st Street station after being suspended early Monday morning.
Another assault was reported in the Bronx earlier this month. Police released surveillance video Monday of an assault in the 174th Street subway station that happened on Dec. 1.
Police say a man walked up to a 58-year-old woman, said an anti-Chinese statement and then slapped her across the face.
The NYPD Transit Bureau addressed the stabbing at the MTA Committee meeting on Monday. They say they are actively working on getting more officers inside the subways and are focused on taking repeat offenders off the streets.