The cases of pediatric inflammatory syndrome were up once again Friday in New York City, with 110 cases. 

“I will wager that is only going to go up and it will be much more widespread than anyone thinks,” said Gov. Andrew Cuomo. 

According to the numbers of pediatric multisystem inflammatory syndrome calculated by the mayor’s office, over half of those with the syndrome have tested positive for COVID-19 or antibodies.

They say most cases are reported in the Bronx, with Brooklyn coming in third. "We cannot panic about it. We have to be looking for it, we have to keep an eye for all the -- for the fever, for all the signs and symptoms that we are talking about so we can address it early,” said Dr. Maria Ramirez. 

Symptoms include persistent fever, rashes, eye redness, swelling and belly pain. 

If you have a concern that your child is showing any of those symptoms, you are asked to call your doctor. 

If you are referred to the hospital, blood work will be done to look for inflammatory markers and treatment. 

"In some cases, intravenous hemoglobin is being used, in some other cases, they are using steroids, so it depends on case by case,” said Dr. Ramirez. 

“Although most of these children are testing positive, I cannot fully say it is secondary to COVID because until we have enough numbers and enough data, anything I saw could be a little rushed,” said Dr. Ramirez. 

She says this is why doctors continue to track and share data.

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The Centers for Disease Control and Prevention has issued a health alert advising health care providers to be on the lookout for COVID-19 cases in children.

Statewide, the CDC says three children have died from the inflammatory syndrome.