Police say a man has been arrested for driving while ability impaired by drugs and alcohol Friday following a crash that seriously injured two people in Holtsville.

Matthew Sheehy was driving a 2022 Dodge pickup eastbound on the Long Island Expressway, 1,000 feet east of Nicolls Road, when the vehicle struck a disabled 2010 Chrysler Town and County parked on the right shoulder at 12:20 a.m.

The Chrysler then crossed the lanes of travel and was struck by a 2018 Honda CRV.

The driver of the Chrysler, Jonathan Thomas, 27, of Mastic Beach, was transported to Stony Brook University Hospital with serious injuries. A passenger in the Honda, whose name is being withheld pending notification of next of kin, was transported to Stony Brook University Hospital in critical condition.

The driver of the Honda, Martin Franco-Soto, 23, of East Hampton, and a passenger, Denise Bustamante-Prieto, were treated and released from Long Island Community Hospital in Patchogue.

Sheehy, 46, of East Setauket, was transported to Stony Brook University Hospital for evaluation.

Sheehy was arrested and charged with driving while ability impaired by drugs and alcohol. He will be arraigned on a later date.

Anyone with information is asked to call authorities at 631-852-6555.